Bryan Johnson's Blueprint Protocol: What Biological Age Tests Does He Use?

Bryan Johnson has become the most visible figure in the longevity movement. The tech entrepreneur turned biohacker spends over $2 million per year on his "Blueprint" anti-aging protocol - and he measures everything. His biological age tests have become almost as famous as he is, with headlines claiming he has the organs of an 18-year-old.

But what tests does Bryan Johnson actually use? Can you access the same measurements? And what can ordinary people learn from his extreme approach to reversing aging?

In this guide, we break down Bryan Johnson's biological age testing, his results, his protocol, and how you can get started with the same core tests he relies on - without spending millions.

Who Is Bryan Johnson?

Bryan Johnson is an American entrepreneur who made his fortune in technology. He founded Braintree, the payment processing company that also owned Venmo, and sold it to PayPal in 2013 for approximately $800 million. After stepping away from the tech world, he founded Kernel (a neurotechnology company) before pivoting to what has become his most public endeavour: Project Blueprint.

Launched in 2021, Blueprint is Johnson's systematic attempt to reverse the aging process in every one of his organs. He has assembled a team of over 30 doctors and health professionals, undergoes hundreds of medical tests per year, and follows a protocol so rigid that virtually every minute of his day is optimised for longevity.

What makes Johnson remarkable in the longevity space is not just his willingness to spend - it is his commitment to transparency. He publishes his protocols, his test results, and his data publicly, allowing anyone to evaluate his approach and adapt elements of it for their own use.

Bryan Johnson's Biological Age Results

Johnson's headline results have made global news. According to his published data:

• Chronological age: 47+ (born 1977)
• Epigenetic biological age: Claims to have achieved the biological age markers of an 18-year-old across multiple organ systems
• DunedinPACE score: Approximately 0.69 - meaning he is aging at roughly 69% of the normal rate, or 31% slower than average
• Fitness age: Reports cardiovascular fitness equivalent to someone decades younger

His DunedinPACE score of 0.69 is particularly striking. For every calendar year that passes, Johnson's body is accumulating only about 8.3 months of biological wear. Over a decade, that means his body ages roughly 6.9 biological years instead of 10 - a significant compounding advantage.

Johnson has also ranked highly on the Rejuvenation Olympics leaderboard, a public competition where participants are ranked by their DunedinPACE scores as measured by TruDiagnostic's TruAge platform.

What Biological Age Tests Does Bryan Johnson Use?

Johnson's testing regime is extraordinarily comprehensive, spanning hundreds of biomarkers across dozens of categories. However, at the core of his aging measurement sits one platform that anyone can access: TruDiagnostic TruAge.

Epigenetic Age Testing: TruDiagnostic TruAge

Johnson uses TruDiagnostic's TruAge testing platform for his primary epigenetic age measurements. This is the same test available to the general public - it is not a custom, millionaire-only tool. TruAge analyses DNA methylation patterns from a blood sample to calculate:

• DunedinPACE - the pace of aging (Johnson's standout metric at ~0.69)
• Multiple biological age clocks - including GrimAge, PhenoAge, Horvath's clock, and others
• SYMPHONYAge - individual organ-system biological ages
• Telomere length - a measure of cellular aging
• Immune cell composition - intrinsic and extrinsic immune age

The TruAge COMPLETE test is available from Lola Health for £380 - the exact same test technology Johnson uses to measure his biological age.

Beyond Epigenetics: Johnson's Full Testing Stack

In addition to epigenetic testing, Johnson's protocol includes an extensive array of other measurements:

Bryan Johnson's Blueprint Protocol: An Overview

Johnson's daily routine is famously regimented. While the full protocol is extraordinarily detailed, here are the key pillars:

Diet

Johnson follows a strict plant-based diet of approximately 1,977 calories per day, consumed in a compressed eating window. His meals are precisely formulated and do not vary - he eats the same foods every day, weighed to the gram. Key components include:

• A "Super Veggie" blend of black lentils, broccoli, cauliflower, mushrooms, garlic, ginger, and hemp seeds
• A "Nutty Pudding" with macadamia nut milk, walnuts, berries, and flaxseed
• Dark chocolate and extra virgin olive oil (for polyphenols)
• Strict avoidance of sugar, processed food, and alcohol

Supplements

Johnson takes over 100 supplements daily. While his stack is extreme, many of the key compounds are well-researched and accessible to anyone:

• NMN (nicotinamide mononucleotide) - an NAD+ precursor linked to cellular energy and longevity
• Omega-3 fatty acids, for cardiovascular and brain health
• Vitamin D3, important for immune function and bone health (especially in the UK where sunlight is limited)
• Magnesium - involved in over 300 enzymatic reactions, often deficient in modern diets
• Creatine - for muscle preservation and cognitive function
• Collagen peptides, for skin elasticity and joint health
• Ashwagandha, an adaptogen for stress and cortisol management
• Cocoa flavanols - for cardiovascular health
• Lycopene, lutein, and zeaxanthin - carotenoids for eye and skin health

Exercise

Johnson exercises for approximately one hour per day, combining:

• High-intensity interval training (HIIT)
• Resistance training (three days per week)
• Flexibility and mobility work
• Cardiovascular training targeting specific heart rate zones

Sleep

Johnson treats sleep as his single most important health intervention. His protocol includes:

• A strict 8:30 PM bedtime, every single night
• No food within several hours of sleeping
• Blue-light blocking glasses in the evening
• A cool, dark, controlled sleep environment
• Continuous monitoring of sleep quality via wearables

Other Interventions

• Red light therapy - for skin health and cellular function
• Strict sun protection - to minimise UV damage to skin
• Oral health protocol - including water flossing and specific dental care products
• Regular blood plasma exchange - an experimental intervention

What Can Regular People Learn from Bryan Johnson?

You do not need $2 million per year to benefit from Johnson's approach. The core insight behind Blueprint is not about money - it is about measurement and consistency. Here are the practical takeaways:

1. Measure Your Baseline

You cannot optimise what you do not measure. Johnson's entire protocol is built on data. The single most impactful step you can take is to get your biological age tested. A TruAge COMPLETE test from Lola Health gives you the same epigenetic age data that Johnson uses, DunedinPACE, organ-system ages, and multiple biological age clocks, for £380.

2. Focus on the Fundamentals

The overwhelming majority of Johnson's results likely come from the basics done consistently and well: a nutrient-dense diet, daily exercise, excellent sleep, and stress management. These cost virtually nothing beyond discipline.

3. Use Evidence-Based Supplements Strategically

Of Johnson's 100+ supplements, a handful have the strongest evidence base: NMN, omega-3, vitamin D, magnesium, and creatine. Starting with these is far more practical than trying to replicate his entire stack.

4. Test, Intervene, Re-Test

This is the most valuable principle. Take your DunedinPACE baseline, implement changes for 3–6 months, then re-test to see what is actually working for your unique biology. Johnson does this constantly at enormous cost - but you can do the same cycle with TruAge testing at a fraction of the price.

The Rejuvenation Olympics: How Others Are Competing on DunedinPACE

Johnson is not alone in his pursuit. The Rejuvenation Olympics is a public leaderboard where participants compete on their rate of aging as measured by DunedinPACE. Participants submit their TruAge test results, and rankings are based on who is aging the slowest.

What is fascinating about the leaderboard is that many of the top performers are not spending millions. They are ordinary people, doctors, engineers, teachers, who have optimised their lifestyle and are tracking their results with the same TruDiagnostic tests available to anyone.

This underscores a important point: you do not need Bryan Johnson's budget to compete with Bryan Johnson's results. You need the right tests, the right interventions, and the discipline to follow through.

How to Get Started: The Same Tests Bryan Johnson Uses

If Bryan Johnson's results have inspired you to measure your own biological age, here is how to begin:

1. Order a TruAge COMPLETE test from Lola Health (£380) - this gives you DunedinPACE, organ-system ages (SYMPHONYAge), OMICmAge, telomere length, immune composition, and multiple epigenetic clocks. It is the same TruDiagnostic platform Johnson uses.
2. Consider a complete blood test - Lola Health offers multiple blood test panels that cover key biomarkers including hormones, inflammation markers, lipids, and organ function. This complements your epigenetic data with actionable blood markers.
3. Implement your interventions - based on your results, focus on the areas with the most room for improvement. Prioritise sleep, nutrition, exercise, and targeted supplementation.
4. Re-test in 3–6 months - use TruAge PACE (a focused DunedinPACE + telomere length test) to track your rate of change. This is the "speedometer check" that tells you whether your interventions are working.

Bryan Johnson vs The Average Person: Cost Comparison

The diminishing returns are significant. The gap between spending £1,000 per year and $2 million per year on longevity is far smaller than you might expect when measured by DunedinPACE outcomes.

Frequently Asked Questions

What biological age test does Bryan Johnson use?

Bryan Johnson uses TruDiagnostic's TruAge platform for his primary epigenetic age measurements, including DunedinPACE (his pace of aging score), multiple biological age clocks (GrimAge, PhenoAge, Horvath), and organ-system ages. The TruAge COMPLETE test is available from Lola Health for £380 - the same test technology Johnson uses.

Can I get the same tests as Bryan Johnson in the UK?

Yes. The core epigenetic age test Johnson relies on, TruDiagnostic TruAge, is available to order from Lola Health. It ships as an at-home blood collection kit directly to your UK address. Lola Health also offers detailed blood test panels that cover many of the same biomarkers Johnson tracks. While some of his more exotic interventions (whole-body MRI, plasma exchange) require specialist clinics, the foundational tests are fully accessible.

What is Bryan Johnson's biological age?

Bryan Johnson claims to have achieved biological age markers equivalent to an 18-year-old across several organ systems, despite being chronologically in his late 40s. His DunedinPACE score, which measures the rate of aging, is approximately 0.69, meaning he is aging at 69% of the normal rate. These results are based on TruDiagnostic TruAge epigenetic testing and his extensive battery of additional medical assessments.

How much does Bryan Johnson spend on anti-aging?

Johnson spends over $2 million per year on his Blueprint protocol. This covers a team of 30+ doctors, hundreds of medical tests, over 100 daily supplements, chef-prepared meals, advanced medical procedures, and experimental therapies. However, the core elements of his approach - epigenetic testing, blood testing, nutrition, exercise, sleep, and key supplements — can be replicated for a few hundred to a few thousand pounds per year.

What supplements does Bryan Johnson take?

Johnson takes over 100 supplements daily. The most notable and evidence-based ones include NMN (an NAD+ precursor), omega-3 fatty acids, vitamin D3, magnesium, creatine, collagen peptides, ashwagandha, cocoa flavanols, lycopene, lutein, and zeaxanthin. While replicating his full stack is impractical for most people, starting with NMN, omega-3, vitamin D, and magnesium covers several of the highest-impact compounds. Always consult a healthcare professional before starting any supplement regimen.

Take the First Step

Bryan Johnson has proven that biological aging can be measured, tracked, and influenced. You do not need his budget to start the journey. The single most impactful step is to measure where you stand today.

Order your TruAge COMPLETE test from Lola Health, the same epigenetic age testing platform Bryan Johnson uses, and discover your biological age, your DunedinPACE, and your organ-system ages. Knowledge is the foundation of every longevity protocol, including Blueprint.